Solvent-Free Preparation of 1,8-Dioxo-Octahydroxanthenes Employing Iron Oxide Nanomaterials

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An efficient solvent-free synthesis of 1,8-dioxo-octahydroxanthenes by using Fe2(SO4)3.7H2O as catalyst

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A novel, simple and environmentally friendly method is reported for the preparation of 1,8-dioxo-octahydroxanthene derivatives by the reaction of dimedon with various aromatic aldehydes, using thiamine chloride  as a recyclable catalyst under solvent-free conditions. This procedure has following benefits; simple workup, moderate reaction times, good yields, and completely compatible with enviro...

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an efficient solvent-free synthesis of 1,8-dioxo-octahydroxanthenes by using fe2(so4)3.7h2o as catalyst

a facile and efficient protocol for the synthesis of 1,8-dioxo-octahydroxanthenes has been developed by one-pot knoevenagel condensation, michael addition and cyclodehydration reaction of dimedone (active methylene carbonyl compound) with aromatic aldehydes in the presence of iron (iii) sulfate hydrate as a solid acidic catalyst under solvent-free conditions. various aromatic aldehydes were uti...

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A highly efficient green synthesis of 1, 8-dioxo-octahydroxanthenes

SmCl3 (20 mol%) has been used as an efficient catalyst for reaction between aromatic aldehydes and 5,5-dimethyl-1,3-cyclohexanedione at 120°C to give 1,8-dioxo-octahydroxanthene derivatives in high yield. The same reaction in water, at room temperature gave only the open chain analogue of 1,8-dioxo-octahydroxanthene. Use of eco-friendly green Lewis acid, readily available catalyst and easy isol...

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ژورنال

عنوان ژورنال: Materials

سال: 2019

ISSN: 1996-1944

DOI: 10.3390/ma12152386